Publications
发表文章
Published Paper:
Kaile Wang*, Yun Yan*, Heba Elgamal*, Jianzhuo Li,
Chenling Tang,
Shanshan Bai, Zhenna Xiao, Emi Sei, Yiyun Lin, Junke Wang, Jessica Montalvan,
Changandeep Nagi, Alastair M. Thompson, Nicholas
Navin# (2024). Single cell genome and
epigenome
co-profiling reveals hardwiring and plasticity in breast cancer.
BioRxiv.
doi: https://doi.org/10.1101/2024.09.06.611519
doi: https://doi.org/10.1101/2024.09.06.611519
Yiyun Lin*, Junke Wang*, Kaile Wang, Shanshan Bai,
Aatish Thennavan,
Runmin Wei, Yun Yan, Jianzhuo Li, Heba Elgamal, Emi Sei, Anna Casasent, Mitchell
Rao, Chenling Tang, Asha S. Multani, Jin Ma, Jessica Montalvan, Chandandeep Nagi,
Sebastian Winocour, Bora Lim, Alastair Thompson, Nicholas Navin#. (2024).
Normal
breast tissues harbour rare populations of aneuploid epithelial cells.
Nature, 636,
663–670.
doi: https://doi.org/10.1038/s41586-024-08129-x
doi: https://doi.org/10.1038/s41586-024-08129-x
Kaile Wang (2024). Revealing genomic secrets
of archival FFPE samples. Tools of the Trade, Nature Reviews
Cancer.
doi: https://doi.org/10.1038/s41568-024-00686-7
doi: https://doi.org/10.1038/s41568-024-00686-7
Zhihao Hou*, Wenpeng Deng*, Alun Li, Ya Zhang, Jianye Chang, Xinyue
Guan, Yuxiao
Chang, Kaile Wang, Xinjie Wang, Jue
Ruan# (2024). A sensitive one-pot ROA assay for rapid miRNA
detection. aBIOTECH, 5, 298–308.
doi: https://doi.org/10.1007/s42994-024-00140-0
doi: https://doi.org/10.1007/s42994-024-00140-0
Kaile Wang*, Tapsi Kumar*, Junke Wang, Darlan Conterno Minussi, Emi
Sei, Jianzhuo Li, Tuan M. Tran, Aatish Thennavan, Min Hu, Anna K. Casasent, Zhenna
Xiao,
Shanshan Bai, Lei Yang, Lorraine M. King, Vandna Shah, Petra Kristel, Carolien L.
van
der Borden, Jeffrey R. Marks, Yuehui Zhao, Amado J. Zurita, Ana Aparicio, Brian
Chapin,
Jie Ye, Jianjun Zhang, Don L. Gibbons, Grand Challenge PRECISION Consortium, Ellinor
Sawyer, Alastair M. Thompson, Andrew Futreal, E. Shelley Hwang, Jelle Wesseling,
Esther
H. Lips, Nicholas E. Navin# (2023). Archival single-cell
genomics reveals persistent subclones during DCIS progression.
Cell, 186(18), 3968–3982.e15.
doi: https://doi.org/10.1016/j.cell.2023.07.024
Highlighted by Cancer Discovery, (2023) 13 (11): OF2; Nature Reviews Cancer, (2024); The Innovation, (2023) 5(1), The Innovation Life (2023) 1(3).
doi: https://doi.org/10.1016/j.cell.2023.07.024
Highlighted by Cancer Discovery, (2023) 13 (11): OF2; Nature Reviews Cancer, (2024); The Innovation, (2023) 5(1), The Innovation Life (2023) 1(3).
Darlan C. Minussi*, Michael D. Nicholson*, Hanghui Ye*, Alexander
Davis, Kaile Wang, Toby Baker, Maxime Tarabichi, Emi Sei,
Haowei
Du, Mashiat Rabbani, Cheng Peng, Min Hu, Shanshan Bai, Yu-wei Lin, Aislyn Schalck,
Asha
Multani, Jin Ma, Thomas O. McDonald, Anna Casasent, Angelica Barrera, Hui Chen, Bora
Lim, Banu Arun, Funda Meric-Bernstam, Peter Van Loo, Franziska
Michor#, Nicholas E. Navin#
(2021).
Breast tumours maintain a reservoir of subclonal diversity during expansion.
Nature, 592, 302–308.
doi: https://doi.org/10.1038/s41586-021-03357-x
doi: https://doi.org/10.1038/s41586-021-03357-x
Kaile Wang*, Zhenna Xiao*, Yun Yan*, Rui Ye, Min Hu,
Shanshan Bai, Emi
Sei, Yawei Qiao, Hui Chen, Bora Lim, Steven H. Lin, Nicholas E.
Navin#(2021). Simple oligonucleotide-based multiplexing of
single-cell chromatin accessibility. Molecular Cell,
81(20),
4319–4332.e10.
doi: https://doi.org/10.1016/j.molcel.2021.09.026
Cover story,Selected as "Best of Molecular Cell Tech 2021"
doi: https://doi.org/10.1016/j.molcel.2021.09.026
Cover story,Selected as "Best of Molecular Cell Tech 2021"
Kaile Wang*, Shujuan Lai, Xiaoxu Yang, Tianqi Zhu,
Xuemei Lu,
Chung-I Wu#, Jue Ruan#
(2017).
Ultrasensitive and high-efficiency screen of de novo low-frequency mutations by
o2n-seq.
Nature Communications, 8, 15335.
doi: https://doi.org/10.1038/ncomms15335
doi: https://doi.org/10.1038/ncomms15335
Li Yu*, Guo-Dong Wang*, Jue Ruan*, Yong-Bin Chen*, Cui-Ping Yang*,
Xue
Cao*, Hong Wu*,
Yan-Hu Liu*, Zheng-Lin Du*, Xiao-Ping Wang*, Jing Yang*, Shao-Chen Cheng*, Li Zhong,
Lu
Wang, Xuan Wang, Jing-Yang Hu, Lu Fang, Bing Bai, Kai-Le Wang,
Na
Yuan, Shi-Fang Wu, Bao-Guo Li, Jin-Guo Zhang, Ye-Qin Yang, Cheng-Lin Zhang,
Yong-Cheng
Long, Hai-Shu Li, Jing-Yuan Yang, David M. Irwin, Oliver A. Ryder, Ying Li,
Chung-I Wu#, Ya-Ping Zhang#
(2016). Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and
processes related to high-altitude adaptation. Nature
Genetics, 48, 947–952.
doi: https://doi.org/10.1038/ng.3615
doi: https://doi.org/10.1038/ng.3615
Kaile Wang, Qin Ma, Lan Jiang, Shujuan Lai, Xuemei
Lu,Yali Hou#, Chung-I
Wu#, Jue Ruan#
(2016). Ultra-precise detection of mutations by droplet-based amplification of
circularized DNA. BMC Genomics, 17, 214.
doi: https://doi.org/10.1186/s12864-016-2480-1
doi: https://doi.org/10.1186/s12864-016-2480-1
Kaile Wang*, Xiaolu Ma*, Xue Zhang, Dafei Wu, Chenyi
Sun, Yazhou Sun,
Xuemei Lu, Chung-I Wu#, Caixia
Guo#, Jue Ruan# (2016). Using
ultra-sensitive next generation sequencing to dissect DNA damage-induced
mutagenesis.
Scientific Reports, 6, 25310.
doi: https://doi.org/10.1038/srep25310
doi: https://doi.org/10.1038/srep25310
Yong Tao*, Zheng Hu*, Shaoping Ling*, Shiou-Hwie Yeh, Weiwei Zhai, Ke
Chen, Chunyan Li,
Yu Wang, Kaile Wang, Hurng-Yi Wang, Eric A. Hungate, Kenan
Onel,
Jiang Liu, Changqing Zeng, Richard R. Hudson, Pei-Jer Chen, Xuemei
Lu#,Chung-I Wu# (2016).
Further genetic diversification in multiple tumors and an evolutionary perspective
on
therapeutics. bioRxiv, 025429.
doi: https://doi.org/10.1101/025429
doi: https://doi.org/10.1101/025429
Patent:
- Nicholas E. Navin, Kaile Wang (2020). Methods and applications for cell barcoding. World Intellectual Property Organization (WIPO) Patent, WO/2020/206285. Filed under Application No. PCT/US2020/026619. Publication date: August 2020
- Jue Ruan, Kaile Wang (2017). Sequencing library, and preparation and use thereof. World Intellectual Property Organization (WIPO) Patent, WO2017054302A1. Filed under Application No. PCT/CN2015/095380. Publication date: April 2017
- Jue Ruan, Kaile Wang, Xu Shen, Xuemei Lu, Chung-I Wu (2016). A kind of DNA cloning method. China National Intellectual Property Administration (CNIPA) Patent, CN105463066B. Filed under Application No. CN201410448896.XA. Publication date: April 2016.
- Zuyu Yang, Kaile Wang, Dafei Wu, Xuemei Lyu, Zhongyi Wu (2016). Taking trace amount DNA as basis two-generation sequencing library construction method. China National Intellectual Property Administration (CNIPA) Patent, CN103938277B. Filed under Application No. 201410158326.7A. Publication date: May 25, 2016.
- Kaile Wang, Jue Ruan, Xuemei Lu, Chung-I Wu (2016). The sequencing library improved and synthesis and applications thereof. China National Intellectual Property Administration (CNIPA) Patent, CN105420348A. Filed under Application No. CN201410448968.0A. Publication date: March 2016.
- Jue Ruan, Kaile Wang, Chung-I Wu, Xuemei Lu (2015). Sequencing library and preparation and use thereof. World Intellectual Property Organization (WIPO) Patent, WO/2015/081890. Filed under Application No. PCT/CN2014/093161. Publication date: June 2015.
- Zuyu Yang, Kaile Wang, Dafei Wu, Xuemei Lyu, Zhongyi Wu (2014). Taking trace amount DNA as basis two-generation sequencing library construction method. China National Intellectual Property Administration (CNIPA) Patent, CN103938277A. Filed under Application No. CN201410158326.7A. Publication date: July 23, 2014